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Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex

Pathogens that traffic in blood, lymphatics, or interstitial fluids must adopt strategies to evade innate immune defenses, notably the complement system. Through recruitment of host regulators of complement to their surface, many pathogens are able to escape complement-mediated attack. The Lyme dise...

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Detalles Bibliográficos
Autores principales: Garcia, Brandon L., Zhi, Hui, Wager, Beau, Höök, Magnus, Skare, Jon T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725857/
https://www.ncbi.nlm.nih.gov/pubmed/26808924
http://dx.doi.org/10.1371/journal.ppat.1005404