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Focal Adhesion Kinase Regulates Fibroblast Migration via Integrin beta-1 and Plays a Central Role in Fibrosis

Lung fibrosis is a major medical problem for the aging population worldwide. Fibroblast migration plays an important role in fibrosis. Focal Adhesion Kinase (FAK) senses the extracellular stimuli and initiates signaling cascades that promote cell migration. This study first examined the dose and tim...

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Detalles Bibliográficos
Autores principales: Zhao, Xue-Ke, Cheng, Yiju, Liang Cheng, Ming, Yu, Lei, Mu, Mao, Li, Hong, Liu, Yang, Zhang, Baofang, Yao, Yumei, Guo, Hui, Wang, Rong, Zhang, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725867/
https://www.ncbi.nlm.nih.gov/pubmed/26763945
http://dx.doi.org/10.1038/srep19276