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Endogenous sulfur dioxide alleviates collagen remodeling via inhibiting TGF-β/Smad pathway in vascular smooth muscle cells

The study was designed to investigate the role of endogenous sulfur dioxide (SO(2)) in collagen remodeling and its mechanisms in vascular smooth muscle cells (VSMCs). Overexpression of endogenous SO(2) synthase aspartate aminotransferase (AAT) 1 or 2 increased SO(2) levels and inhibited collagen I a...

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Detalles Bibliográficos
Autores principales: Huang, Yaqian, Shen, Zhizhou, Chen, Qinghua, Huang, Pan, Zhang, Heng, Du, Shuxu, Geng, Bin, Zhang, Chunyu, Li, Kun, Tang, Chaoshu, Du, Junbao, Jin, Hongfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725894/
https://www.ncbi.nlm.nih.gov/pubmed/26762477
http://dx.doi.org/10.1038/srep19503