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α-Synuclein and huntingtin exon 1 amyloid fibrils bind laterally to the cellular membrane
Fibrillar aggregates involved in neurodegenerative diseases have the ability to spread from one cell to another in a prion-like manner. The underlying molecular mechanisms, in particular the binding mode of the fibrils to cell membranes, are poorly understood. In this work we decipher the modality b...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725933/ https://www.ncbi.nlm.nih.gov/pubmed/26757959 http://dx.doi.org/10.1038/srep19180 |