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Role of Purinergic Receptor Expression and Function for Reduced Responsiveness to Adenosine Diphosphate in Washed Human Platelets

BACKGROUND: Washing of platelets is an important procedure commonly used for experimental studies, e.g. in cardiovascular research. As a known phenomenon, responsiveness to adenosine diphosphate (ADP) is reduced in washed platelets, although underlying molecular mechanisms—potentially interfering wi...

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Detalles Bibliográficos
Autores principales: Koessler, Juergen, Hermann, Stephanie, Weber, Katja, Koessler, Angela, Kuhn, Sabine, Boeck, Markus, Kobsar, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725951/
https://www.ncbi.nlm.nih.gov/pubmed/26808867
http://dx.doi.org/10.1371/journal.pone.0147370