Trading off stability against activity in extremophilic aldolases

Understanding enzyme stability and activity in extremophilic organisms is of great biotechnological interest, but many questions are still unsolved. Using 2-deoxy-D-ribose-5-phosphate aldolase (DERA) as model enzyme, we have evaluated structural and functional characteristics of different orthologs...

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Detalles Bibliográficos
Autores principales: Dick, Markus, Weiergräber, Oliver H., Classen, Thomas, Bisterfeld, Carolin, Bramski, Julia, Gohlke, Holger, Pietruszka, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725968/
https://www.ncbi.nlm.nih.gov/pubmed/26783049
http://dx.doi.org/10.1038/srep17908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725968/
https://www.ncbi.nlm.nih.gov/pubmed/26783049
http://dx.doi.org/10.1038/srep17908

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