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Trading off stability against activity in extremophilic aldolases
Understanding enzyme stability and activity in extremophilic organisms is of great biotechnological interest, but many questions are still unsolved. Using 2-deoxy-D-ribose-5-phosphate aldolase (DERA) as model enzyme, we have evaluated structural and functional characteristics of different orthologs...
Autores principales: | Dick, Markus, Weiergräber, Oliver H., Classen, Thomas, Bisterfeld, Carolin, Bramski, Julia, Gohlke, Holger, Pietruszka, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725968/ https://www.ncbi.nlm.nih.gov/pubmed/26783049 http://dx.doi.org/10.1038/srep17908 |
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