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Interplay Between Intracellular Ca(2+) Oscillations and Ca(2+)-stimulated Mitochondrial Metabolism

Oscillations of cytosolic Ca(2+) concentration are a widespread mode of signalling. Oscillatory spikes rely on repetitive exchanges of Ca(2+) between the endoplasmic reticulum (ER) and the cytosol, due to the regulation of inositol 1,4,5-trisphosphate receptors. Mitochondria also sequester and relea...

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Detalles Bibliográficos
Autores principales: Wacquier, Benjamin, Combettes, Laurent, Van Nhieu, Guy Tran, Dupont, Geneviève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725975/
https://www.ncbi.nlm.nih.gov/pubmed/26776859
http://dx.doi.org/10.1038/srep19316