A target-protection mechanism of antibiotic resistance at atomic resolution: insights into FusB-type fusidic acid resistance

Antibiotic resistance in clinically important bacteria can be mediated by proteins that physically associate with the drug target and act to protect it from the inhibitory effects of an antibiotic. We present here the first detailed structural characterization of such a target protection mechanism m...

Descripción completa

Detalles Bibliográficos
Autores principales: Tomlinson, Jennifer H., Thompson, Gary S., Kalverda, Arnout P., Zhuravleva, Anastasia, O’Neill, Alex J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725979/
https://www.ncbi.nlm.nih.gov/pubmed/26781961
http://dx.doi.org/10.1038/srep19524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725979/
https://www.ncbi.nlm.nih.gov/pubmed/26781961
http://dx.doi.org/10.1038/srep19524

Ejemplares similares