Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm’s canal endothelial cells

Ripasudil hydrochloride hydrate (K-115), a specific Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor, was the first ophthalmic solution developed for the treatment of glaucoma and ocular hypertension in Japan. Topical administration of K-115 decreased intraocular pressure (IOP)...

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Detalles Bibliográficos
Autores principales: Kaneko, Yoshio, Ohta, Masayuki, Inoue, Toshihiro, Mizuno, Ken, Isobe, Tomoyuki, Tanabe, Sohei, Tanihara, Hidenobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725980/
https://www.ncbi.nlm.nih.gov/pubmed/26782355
http://dx.doi.org/10.1038/srep19640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725980/
https://www.ncbi.nlm.nih.gov/pubmed/26782355
http://dx.doi.org/10.1038/srep19640

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