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Chemical dampening of Ly6C(hi) monocytes in the periphery produces anti-depressant effects in mice
The involvement of systemic immunity in depression pathogenesis promises a periphery-targeting paradigm in novel anti-depressant discovery. However, relatively little is known about druggable targets in the periphery for mental and behavioral control. Here we report that targeting Ly6C(hi) monocytes...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725984/ https://www.ncbi.nlm.nih.gov/pubmed/26783261 http://dx.doi.org/10.1038/srep19406 |