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NRF2 Is a Key Target for Prevention of Noise-Induced Hearing Loss by Reducing Oxidative Damage of Cochlea

Noise-induced hearing loss (NIHL) is one of the most common sensorineural hearing deficits. Recent studies have demonstrated that the pathogenesis of NIHL is closely related to ischemia-reperfusion injury of cochlea, which is caused by blood flow decrease and free radical production due to excessive...

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Detalles Bibliográficos
Autores principales: Honkura, Yohei, Matsuo, Hirotaka, Murakami, Shohei, Sakiyama, Masayuki, Mizutari, Kunio, Shiotani, Akihiro, Yamamoto, Masayuki, Morita, Ichiro, Shinomiya, Nariyoshi, Kawase, Tetsuaki, Katori, Yukio, Motohashi, Hozumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726010/
https://www.ncbi.nlm.nih.gov/pubmed/26776972
http://dx.doi.org/10.1038/srep19329