Gel electrophoresis in a polyvinylalcohol coated fused silica capillary for purity assessment of modified and secondary-structured oligo- and polyribonucleotides

Application of a polyvinylalcohol-coated (PVA-coated) capillary in capillary gel electrophoresis (CGE) enables the selective separation of oligoribonucleotides and their modifications at high resolution. Quality assessment of shorter oligomers of small interfering RNA (siRNA) is of key importance fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Barciszewska, Martyna, Sucha, Agnieszka, Bałabańska, Sandra, Chmielewski, Marcin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726012/
https://www.ncbi.nlm.nih.gov/pubmed/26777121
http://dx.doi.org/10.1038/srep19437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726012/
https://www.ncbi.nlm.nih.gov/pubmed/26777121
http://dx.doi.org/10.1038/srep19437

Ejemplares similares