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Rspo1-activated signalling molecules are sufficient to induce ovarian differentiation in XY medaka (Oryzias latipes)

In contrast to our understanding of testicular differentiation, ovarian differentiation is less well understood in vertebrates. In mammals, R-spondin1 (Rspo1), an activator of Wnt/β-catenin signaling pathway, is located upstream of the female sex determination pathway. However, the functions of Rspo...

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Detalles Bibliográficos
Autores principales: Zhou, Linyan, Charkraborty, Tapas, Zhou, Qian, Mohapatra, Sipra, Nagahama, Yoshitaka, Zhang, Yueguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726049/
https://www.ncbi.nlm.nih.gov/pubmed/26782368
http://dx.doi.org/10.1038/srep19543