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Rspo1-activated signalling molecules are sufficient to induce ovarian differentiation in XY medaka (Oryzias latipes)
In contrast to our understanding of testicular differentiation, ovarian differentiation is less well understood in vertebrates. In mammals, R-spondin1 (Rspo1), an activator of Wnt/β-catenin signaling pathway, is located upstream of the female sex determination pathway. However, the functions of Rspo...
Autores principales: | Zhou, Linyan, Charkraborty, Tapas, Zhou, Qian, Mohapatra, Sipra, Nagahama, Yoshitaka, Zhang, Yueguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726049/ https://www.ncbi.nlm.nih.gov/pubmed/26782368 http://dx.doi.org/10.1038/srep19543 |
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