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Structural Elucidation of a Carnosine-Acrolein Adduct and its Quantification in Human Urine Samples

Aldehydes accumulate in inflammation, during myocardial infarction and have been associated with pain symptoms. One pathway of aldehyde detoxification is the conjugation with carnosine. A 3-methylpyridinium carnosine adduct from the reaction of carnosine and acrolein was characterized using extensiv...

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Detalles Bibliográficos
Autores principales: Bispo, Vanderson S., de Arruda Campos, Ivan P., Di Mascio, Paolo, Medeiros, Marisa H. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726056/
https://www.ncbi.nlm.nih.gov/pubmed/26783107
http://dx.doi.org/10.1038/srep19348