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The RNA chaperone activity of the Trypanosoma brucei editosome raises the dynamic of bound pre-mRNAs

Mitochondrial transcript maturation in African trypanosomes requires an RNA editing reaction that is characterized by the insertion and deletion of U-nucleotides into otherwise non-functional mRNAs. The reaction is catalyzed by editosomes and requires guide (g)RNAs as templates. Recent data demonstr...

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Detalles Bibliográficos
Autores principales: Leeder, W.-Matthias, Voigt, Christin, Brecht, Michael, Göringer, H. Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726059/
https://www.ncbi.nlm.nih.gov/pubmed/26782631
http://dx.doi.org/10.1038/srep19309