Cargando…

Inhibiting the immunoproteasome exacerbates the pathogenesis of systemic Candida albicans infection in mice

Apart from its role in MHC class I antigen processing, the immunoproteasome has recently been implicated in the modulation of T helper cell differentiation under polarizing conditions in vitro and in the pathogenesis of autoimmune diseases in vivo. In this study, we investigated the influence of LMP...

Descripción completa

Detalles Bibliográficos
Autores principales: Mundt, Sarah, Basler, Michael, Buerger, Stefanie, Engler, Harald, Groettrup, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726078/
https://www.ncbi.nlm.nih.gov/pubmed/26776888
http://dx.doi.org/10.1038/srep19434