Cargando…

Olanzapine Prevents the PCP-induced Reduction in the Neurite Outgrowth of Prefrontal Cortical Neurons via NRG1

Accumulating evidence suggests that reducing neurite outgrowth and synaptic plasticity plays a critical role in the pathology of cognitive deficits in schizophrenia. The N-methyl-D-aspartate receptor antagonist phencyclidine (PCP) can induce symptoms of schizophrenia as well as reduce dendritic spin...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Qingsheng, Yu, Yinghua, Huang, Xu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726088/
https://www.ncbi.nlm.nih.gov/pubmed/26781398
http://dx.doi.org/10.1038/srep19581