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Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs

We performed genome-wide meta-analysis of lipid traits on three samples of Mexican and Mexican American ancestry comprising 4,383 individuals, and followed up significant and highly suggestive associations in three additional Hispanic samples comprising 7,876 individuals. Genome-wide significant sig...

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Detalles Bibliográficos
Autores principales: Below, Jennifer E., Parra, Esteban J., Gamazon, Eric R., Torres, Jason, Krithika, S., Candille, Sophie, Lu, Yingchang, Manichakul, Ani, Peralta-Romero, Jesus, Duan, Qing, Li, Yun, Morris, Andrew P., Gottesman, Omri, Bottinger, Erwin, Wang, Xin-Qun, Taylor, Kent D., Ida Chen, Y.-D., Rotter, Jerome I., Rich, Stephen S., Loos, Ruth J. F., Tang, Hua, Cox, Nancy J., Cruz, Miguel, Hanis, Craig L., Valladares-Salgado, Adan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726092/
https://www.ncbi.nlm.nih.gov/pubmed/26780889
http://dx.doi.org/10.1038/srep19429