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DSF Guided Refolding As A Novel Method Of Protein Production

The Anfinsen hypothesis, the demonstration of which led to the Nobel prize in Chemistry, posits that all information required to determine a proteins’ three dimensional structure is contained within its amino acid sequence. This suggests that it should be possible, in theory, to fold any protein in...

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Detalles Bibliográficos
Autores principales: Biter, Amadeo B., de la Peña, Andres H., Thapar, Roopa, Lin, Jean Z., Phillips, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726114/
https://www.ncbi.nlm.nih.gov/pubmed/26783150
http://dx.doi.org/10.1038/srep18906