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Peptides in headlock – a novel high-affinity and versatile peptide-binding nanobody for proteomics and microscopy
Nanobodies are highly valuable tools for numerous bioanalytical and biotechnical applications. Here, we report the characterization of a nanobody that binds a short peptide epitope with extraordinary affinity. Structural analysis reveals an unusual binding mode where the extended peptide becomes par...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726124/ https://www.ncbi.nlm.nih.gov/pubmed/26791954 http://dx.doi.org/10.1038/srep19211 |