Study of Arsenic Sulfide in Solid Tumor Cells Reveals Regulation of Nuclear Factors of Activated T-cells by PML and p53

Arsenic sulfide (AS) has excellent cytotoxic activity in acute promyelocytic leukemia (APL) but its activity in solid tumors remains to be explored. Here we show that AS and cyclosporine A (CsA) exerted synergistic inhibitory effect on cell growth and c-Myc expression in HCT116 cells. AS inhibited t...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Wenping, Tong, Yingying, Zhang, Xiuli, Pan, Minggui, Chen, Siyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726130/
https://www.ncbi.nlm.nih.gov/pubmed/26795951
http://dx.doi.org/10.1038/srep19793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726130/
https://www.ncbi.nlm.nih.gov/pubmed/26795951
http://dx.doi.org/10.1038/srep19793

Ejemplares similares