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c.A2456C-substitution in Pck1 changes the enzyme kinetic and functional properties modifying fat distribution in pigs

Cytosolic phosphoenolpyruvate carboxykinase, PCK1, is one of the main regulatory enzymes of gluconeogenesis and glyceroneogenesis. The substitution of a single amino acid (Met139Leu) in PCK1 as a consequence of a single nucleotide polymorphism (SNP), c.A2456C, is associated in the pig to a negative...

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Detalles Bibliográficos
Autores principales: Latorre, Pedro, Burgos, Carmen, Hidalgo, Jorge, Varona, Luis, Carrodeguas, José Alberto, López-Buesa, Pascual
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726144/
https://www.ncbi.nlm.nih.gov/pubmed/26792594
http://dx.doi.org/10.1038/srep19617