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c.A2456C-substitution in Pck1 changes the enzyme kinetic and functional properties modifying fat distribution in pigs
Cytosolic phosphoenolpyruvate carboxykinase, PCK1, is one of the main regulatory enzymes of gluconeogenesis and glyceroneogenesis. The substitution of a single amino acid (Met139Leu) in PCK1 as a consequence of a single nucleotide polymorphism (SNP), c.A2456C, is associated in the pig to a negative...
Autores principales: | Latorre, Pedro, Burgos, Carmen, Hidalgo, Jorge, Varona, Luis, Carrodeguas, José Alberto, López-Buesa, Pascual |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726144/ https://www.ncbi.nlm.nih.gov/pubmed/26792594 http://dx.doi.org/10.1038/srep19617 |
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