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Mechanisms Restricting Diffusion of Intracellular cAMP
Although numerous receptors stimulate cAMP production in a wide array of cells, many elicit distinct, highly localized responses, implying that the subcellular distribution of cAMP is not uniform. One often used explanation is that phosphodiesterases, which breakdown cAMP, act as functional barriers...
Autores principales: | Agarwal, Shailesh R., Clancy, Colleen E., Harvey, Robert D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726171/ https://www.ncbi.nlm.nih.gov/pubmed/26795432 http://dx.doi.org/10.1038/srep19577 |
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