Blocking protein phosphatase 2A signaling prevents endothelial-to-mesenchymal transition and renal fibrosis: a peptide-based drug therapy

Endothelial-to-mesenchymal transition (EndMT) contributes to the emergence of fibroblasts and plays a significant role in renal interstitial fibrosis. Protein phosphatase 2A (PP2A) is a major serine/threonine protein phosphatase in eukaryotic cells and regulates many signaling pathways. However, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Yuanjun, Guo, Yanyan, Liu, Ping, Zeng, Rui, Ning, Yong, Pei, Guangchang, Li, Yueqiang, Chen, Meixue, Guo, Shuiming, Li, Xiaoqing, Han, Min, Xu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726189/
https://www.ncbi.nlm.nih.gov/pubmed/26805394
http://dx.doi.org/10.1038/srep19821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726189/
https://www.ncbi.nlm.nih.gov/pubmed/26805394
http://dx.doi.org/10.1038/srep19821

Ejemplares similares