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Blocking protein phosphatase 2A signaling prevents endothelial-to-mesenchymal transition and renal fibrosis: a peptide-based drug therapy

Endothelial-to-mesenchymal transition (EndMT) contributes to the emergence of fibroblasts and plays a significant role in renal interstitial fibrosis. Protein phosphatase 2A (PP2A) is a major serine/threonine protein phosphatase in eukaryotic cells and regulates many signaling pathways. However, the...

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Detalles Bibliográficos
Autores principales:	Deng, Yuanjun, Guo, Yanyan, Liu, Ping, Zeng, Rui, Ning, Yong, Pei, Guangchang, Li, Yueqiang, Chen, Meixue, Guo, Shuiming, Li, Xiaoqing, Han, Min, Xu, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726189/ https://www.ncbi.nlm.nih.gov/pubmed/26805394 http://dx.doi.org/10.1038/srep19821

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