Characterizing the Conformational Landscape of Flavivirus Fusion Peptides via Simulation and Experiment

Conformational changes in the envelope proteins of flaviviruses help to expose the highly conserved fusion peptide (FP), a region which is critical to membrane fusion and host cell infection, and which represents a significant target for antiviral drugs and antibodies. In principle, extended timesca...

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Detalles Bibliográficos
Autores principales: Marzinek, Jan K., Lakshminarayanan, Rajamani, Goh, Eunice, Huber, Roland G., Panzade, Sadhana, Verma, Chandra, Bond, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726195/
https://www.ncbi.nlm.nih.gov/pubmed/26785994
http://dx.doi.org/10.1038/srep19160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726195/
https://www.ncbi.nlm.nih.gov/pubmed/26785994
http://dx.doi.org/10.1038/srep19160

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