Cargando…
Characterizing the Conformational Landscape of Flavivirus Fusion Peptides via Simulation and Experiment
Conformational changes in the envelope proteins of flaviviruses help to expose the highly conserved fusion peptide (FP), a region which is critical to membrane fusion and host cell infection, and which represents a significant target for antiviral drugs and antibodies. In principle, extended timesca...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726195/ https://www.ncbi.nlm.nih.gov/pubmed/26785994 http://dx.doi.org/10.1038/srep19160 |