Ca(2+) dynamics in oocytes from naturally-aged mice

The ability of human metaphase-II arrested eggs to activate following fertilisation declines with advancing maternal age. Egg activation is triggered by repetitive increases in intracellular Ca(2+) concentration ([Ca(2+)](i)) in the ooplasm as a result of sperm-egg fusion. We therefore hypothesised...

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Detalles Bibliográficos
Autores principales: Haverfield, Jenna, Nakagawa, Shoma, Love, Daniel, Tsichlaki, Elina, Nomikos, Michail, Lai, F. Anthony, Swann, Karl, FitzHarris, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726220/
https://www.ncbi.nlm.nih.gov/pubmed/26785810
http://dx.doi.org/10.1038/srep19357