Ca(2+) dynamics in oocytes from naturally-aged mice
The ability of human metaphase-II arrested eggs to activate following fertilisation declines with advancing maternal age. Egg activation is triggered by repetitive increases in intracellular Ca(2+) concentration ([Ca(2+)](i)) in the ooplasm as a result of sperm-egg fusion. We therefore hypothesised...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726220/ https://www.ncbi.nlm.nih.gov/pubmed/26785810 http://dx.doi.org/10.1038/srep19357 |