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Crystal structure and SUMO binding of Slx1-Slx4 complex

The SLX1-SLX4 complex is a structure-specific endonuclease that cleaves branched DNA structures and plays significant roles in DNA recombination and repair in eukaryotic cells. The heterodimeric interaction between SLX1 and SLX4 is essential for the endonuclease activity of SLX1. Here, we present th...

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Detalles Bibliográficos
Autores principales: Lian, Fu-Ming, Xie, Si, Qian, Chengmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726241/
https://www.ncbi.nlm.nih.gov/pubmed/26787556
http://dx.doi.org/10.1038/srep19331