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Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition

The mortality and morbidity rates of pancreatic cancer are high because of its extremely invasive and metastatic nature. Its lack of symptoms, late diagnosis and chemo–resistance and the ineffective treatment modalities warrant the development of new chemo–therapeutic agents for pancreatic cancer. A...

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Detalles Bibliográficos
Autores principales: Subramani, Ramadevi, Gonzalez, Elizabeth, Arumugam, Arunkumar, Nandy, Sushmita, Gonzalez, Viviana, Medel, Joshua, Camacho, Fernando, Ortega, Andrew, Bonkoungou, Sandrine, Narayan, Mahesh, Dwivedi, Alok kumar, Lakshmanaswamy, Rajkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726267/
https://www.ncbi.nlm.nih.gov/pubmed/26804739
http://dx.doi.org/10.1038/srep19819