Scaling-up Fermentation of Pichia pastoris to demonstration-scale using new methanol-feeding strategy and increased air pressure instead of pure oxygen supplement

Scaling-up of high-cell-density fermentation (HCDF) of Pichia pastoris from the lab or pilot scale to the demonstration scale possesses great significance because the latter is the final technological hurdle in the decision to go commercial. However, related investigations have rarely been reported....

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Detalles Bibliográficos
Autores principales: Liu, Wan-Cang, Gong, Ting, Wang, Qing-Hua, Liang, Xiao, Chen, Jing-Jing, Zhu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726300/
https://www.ncbi.nlm.nih.gov/pubmed/26790977
http://dx.doi.org/10.1038/srep18439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726300/
https://www.ncbi.nlm.nih.gov/pubmed/26790977
http://dx.doi.org/10.1038/srep18439

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