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Mesenchymal stem cells maintain their defining stem cell characteristics after treatment with cisplatin

Mesenchymal stem cells (MSCs) aid the regeneration of tissues damaged by treatment with cisplatin. However, the effects of this cytotoxic drug on the stem cells have been largely unknown. Here we demonstrate that human bone marrow-derived MSCs are relatively resistant to cisplatin treatment and show...

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Detalles Bibliográficos
Autores principales: Nicolay, Nils H., Perez, Ramon Lopez, Rühle, Alexander, Trinh, Thuy, Sisombath, Sonevisay, Weber, Klaus-Josef, Ho, Anthony D., Debus, Jürgen, Saffrich, Rainer, Huber, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726328/
https://www.ncbi.nlm.nih.gov/pubmed/26805490
http://dx.doi.org/10.1038/srep20035