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Liver sinusoidal endothelial cells induce tolerance of autoreactive CD4(+) recent thymic emigrants

The liver is a unique lymphoid organ whose microenvironment is biased towards tolerance induction. We previously found that a proportion of CD4(+) autoreactive recent thymic emigrants (RTEs) retained in the liver after thymic egress and acquired IL-10 producing capability. To investigate the toleran...

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Detalles Bibliográficos
Autores principales: Xu, Xi, Jin, Rong, Li, Mingyang, Wang, Ke, Zhang, Shusong, Hao, Jie, Sun, Xiuyuan, Zhang, Yu, Wu, Hounan, Zhang, Jun, Ge, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726350/
https://www.ncbi.nlm.nih.gov/pubmed/26794038
http://dx.doi.org/10.1038/srep19861