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Liver sinusoidal endothelial cells induce tolerance of autoreactive CD4(+) recent thymic emigrants
The liver is a unique lymphoid organ whose microenvironment is biased towards tolerance induction. We previously found that a proportion of CD4(+) autoreactive recent thymic emigrants (RTEs) retained in the liver after thymic egress and acquired IL-10 producing capability. To investigate the toleran...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726350/ https://www.ncbi.nlm.nih.gov/pubmed/26794038 http://dx.doi.org/10.1038/srep19861 |