Development of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic kras(V12) expression in transgenic zebrafish

Here we report a new transgenic expression system by combination of liver-specific expression, mifepristone induction and Cre-loxP recombination to conditionally control the expression of oncogenic kras(V12). This transgenic system allowed expression of kras(V12) specifically in the liver by a brief...

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Detalles Bibliográficos
Autores principales: Nguyen, Anh Tuan, Koh, Vivien, Spitsbergen, Jan M., Gong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726387/
https://www.ncbi.nlm.nih.gov/pubmed/26790949
http://dx.doi.org/10.1038/srep19559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726387/
https://www.ncbi.nlm.nih.gov/pubmed/26790949
http://dx.doi.org/10.1038/srep19559

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