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Two Genetic Variations in the IRF8 region are associated with Behçet’s disease in Han Chinese

Several modulatory factors in the TLR signaling pathway including IRF3, IRF7, IRF8, TRIM20, MYD88 and NF-κB1 have been associated with autoimmune disease. In this study, we investigated the association of 13 SNPs for these genes with Behçet’s disease (BD) and Vogt-Koyanagi-Harada (VKH) syndrome usin...

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Detalles Bibliográficos
Autores principales: Jiang, Yanni, Wang, Hong, Yu, Hongsong, Li, Lin, Xu, Dengfeng, Hou, Shengping, Kijlstra, Aize, Yang, Peizeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726413/
https://www.ncbi.nlm.nih.gov/pubmed/26794091
http://dx.doi.org/10.1038/srep19651