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Distinct mutation accumulation rates among tissues determine the variation in cancer risk

Cancer is believed to be a result of accumulated mutations. However, this concept has not been fully confirmed owing to the impossibility of tracking down the ancestral somatic cell. We sought to verify the concept by exploring the correlation between cancer risk and mutation accumulation among diff...

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Detalles Bibliográficos
Autores principales: Hao, Dapeng, Wang, Li, Di, Li-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726417/
https://www.ncbi.nlm.nih.gov/pubmed/26785814
http://dx.doi.org/10.1038/srep19458