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Distinct mutation accumulation rates among tissues determine the variation in cancer risk
Cancer is believed to be a result of accumulated mutations. However, this concept has not been fully confirmed owing to the impossibility of tracking down the ancestral somatic cell. We sought to verify the concept by exploring the correlation between cancer risk and mutation accumulation among diff...
Autores principales: | Hao, Dapeng, Wang, Li, Di, Li-jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726417/ https://www.ncbi.nlm.nih.gov/pubmed/26785814 http://dx.doi.org/10.1038/srep19458 |
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