Predicting DNA Methylation State of CpG Dinucleotide Using Genome Topological Features and Deep Networks

The hypo- or hyper-methylation of the human genome is one of the epigenetic features of leukemia. However, experimental approaches have only determined the methylation state of a small portion of the human genome. We developed deep learning based (stacked denoising autoencoders, or SdAs) software na...

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Detalles Bibliográficos
Autores principales: Wang, Yiheng, Liu, Tong, Xu, Dong, Shi, Huidong, Zhang, Chaoyang, Mo, Yin-Yuan, Wang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726425/
https://www.ncbi.nlm.nih.gov/pubmed/26797014
http://dx.doi.org/10.1038/srep19598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726425/
https://www.ncbi.nlm.nih.gov/pubmed/26797014
http://dx.doi.org/10.1038/srep19598

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