Cargando…

Essential role of proteasomes in maintaining self-renewal in neural progenitor cells

Protein turnover and homeostasis are regulated by the proteasomal system, which is critical for cell function and viability. Pluripotency of stem cells also relies on normal proteasomal activity that mitigates senescent phenotypes induced by intensive cell replications, as previously demonstrated in...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Yunhe, Liu, Xueqin, He, Zebin, Niu, Xiaojie, Shi, Weijun, Ding, Jian M., Zhang, Li, Yuan, Tifei, Li, Ang, Yang, Wulin, Lu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726439/
https://www.ncbi.nlm.nih.gov/pubmed/26804982
http://dx.doi.org/10.1038/srep19752