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Impact of Genetic Reduction of NMNAT2 on Chemotherapy-Induced Losses in Cell Viability In Vitro and Peripheral Neuropathy In Vivo

Nicotinamide mononucleotide adenylyl transferases (NMNATs) are essential neuronal maintenance factors postulated to preserve neuronal function and protect against axonal degeneration in various neurodegenerative disease states. We used in vitro and in vivo approaches to assess the impact of NMNAT2 r...

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Detalles Bibliográficos
Autores principales: Slivicki, Richard A., Ali, Yousuf O., Lu, Hui-Chen, Hohmann, Andrea G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726514/
https://www.ncbi.nlm.nih.gov/pubmed/26808812
http://dx.doi.org/10.1371/journal.pone.0147620