Cargando…

Adaptive Landscape by Environment Interactions Dictate Evolutionary Dynamics in Models of Drug Resistance

The adaptive landscape analogy has found practical use in recent years, as many have explored how their understanding can inform therapeutic strategies that subvert the evolution of drug resistance. A major barrier to applications of these concepts is a lack of detail concerning how the environment...

Descripción completa

Detalles Bibliográficos
Autores principales: Ogbunugafor, C. Brandon, Wylie, C. Scott, Diakite, Ibrahim, Weinreich, Daniel M., Hartl, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726534/
https://www.ncbi.nlm.nih.gov/pubmed/26808374
http://dx.doi.org/10.1371/journal.pcbi.1004710