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Adaptive Landscape by Environment Interactions Dictate Evolutionary Dynamics in Models of Drug Resistance
The adaptive landscape analogy has found practical use in recent years, as many have explored how their understanding can inform therapeutic strategies that subvert the evolution of drug resistance. A major barrier to applications of these concepts is a lack of detail concerning how the environment...
Autores principales: | Ogbunugafor, C. Brandon, Wylie, C. Scott, Diakite, Ibrahim, Weinreich, Daniel M., Hartl, Daniel L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726534/ https://www.ncbi.nlm.nih.gov/pubmed/26808374 http://dx.doi.org/10.1371/journal.pcbi.1004710 |
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