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Ceramide Induces Human Hepcidin Gene Transcription through JAK/STAT3 Pathway

Changes in lipid metabolism and iron content are observed in the livers of patients with fatty liver disease. The expression of hepcidin, an iron-regulatory and acute phase protein synthesized by the liver, is also modulated. The potential interaction of lipid and iron metabolism is largely unknown....

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Detalles Bibliográficos
Autores principales: Lu, Sizhao, Natarajan, Sathish Kumar, Mott, Justin L., Kharbanda, Kusum K., Harrison-Findik, Duygu Dee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726556/
https://www.ncbi.nlm.nih.gov/pubmed/26807955
http://dx.doi.org/10.1371/journal.pone.0147474