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A Single-Nucleotide Polymorphism in ABCC4 Is Associated with Tenofovir-Related Beta2-Microglobulinuria in Thai Patients with HIV-1 Infection

BACKGROUND: In Thailand, the combined generic anti-retroviral drug stavudine/lamivudine/nevirapine (d4T/3TC/NVP) has been used to treat human immunodeficiency virus (HIV)-infected individuals since 2001. Due to relatively frequent adverse effects, d4T gradually has been replaced with tenofovir disop...

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Detalles Bibliográficos
Autores principales: Likanonsakul, Sirirat, Suntisuklappon, Bussakorn, Nitiyanontakij, Ravee, Prasithsirikul, Wisit, Nakayama, Emi E., Shioda, Tatsuo, Sangsajja, Chariya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726597/
https://www.ncbi.nlm.nih.gov/pubmed/26807589
http://dx.doi.org/10.1371/journal.pone.0147724