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Canalization of genetic and pharmacological perturbations in developing primary neuronal activity patterns

The function of the nervous system depends on the integrity of synapses and the patterning of electrical activity in brain circuits. The rapid advances in genome sequencing reveal a large number of mutations disrupting synaptic proteins, which potentially result in diseases known as synaptopathies....

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Detalles Bibliográficos
Autores principales: Charlesworth, Paul, Morton, Andrew, Eglen, Stephen J., Komiyama, Noboru H., Grant, Seth G.N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726661/
https://www.ncbi.nlm.nih.gov/pubmed/26211975
http://dx.doi.org/10.1016/j.neuropharm.2015.07.027