Cargando…
Canalization of genetic and pharmacological perturbations in developing primary neuronal activity patterns
The function of the nervous system depends on the integrity of synapses and the patterning of electrical activity in brain circuits. The rapid advances in genome sequencing reveal a large number of mutations disrupting synaptic proteins, which potentially result in diseases known as synaptopathies....
Autores principales: | Charlesworth, Paul, Morton, Andrew, Eglen, Stephen J., Komiyama, Noboru H., Grant, Seth G.N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726661/ https://www.ncbi.nlm.nih.gov/pubmed/26211975 http://dx.doi.org/10.1016/j.neuropharm.2015.07.027 |
Ejemplares similares
-
Quantitative differences in developmental profiles of spontaneous activity in cortical and hippocampal cultures
por: Charlesworth, Paul, et al.
Publicado: (2015) -
A comparison of computational methods for detecting bursts in neuronal spike trains and their application to human stem cell-derived neuronal networks
por: Cotterill, Ellese, et al.
Publicado: (2016) -
Knockdown of mental disorder susceptibility genes disrupts neuronal network physiology in vitro
por: MacLaren, Erik J., et al.
Publicado: (2011) -
Evolution of NMDA receptor cytoplasmic interaction domains: implications for organisation of synaptic signalling complexes
por: Ryan, Tomás J, et al.
Publicado: (2008) -
Automated design of genomic Southern blot probes
por: Croning, Mike DR, et al.
Publicado: (2010)