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Structure of the Intermediate Filament-Binding Region of Desmoplakin

Desmoplakin (DP) is a cytoskeletal linker protein that connects the desmosomal cadherin/plakoglobin/plakophilin complex to intermediate filaments (IFs). The C-terminal region of DP (DPCT) mediates IF binding, and contains three plakin repeat domains (PRDs), termed PRD-A, PRD-B and PRD-C. Previous cr...

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Detalles Bibliográficos
Autores principales: Kang, Hyunook, Weiss, Thomas M., Bang, Injin, Weis, William I., Choi, Hee-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726743/
https://www.ncbi.nlm.nih.gov/pubmed/26808545
http://dx.doi.org/10.1371/journal.pone.0147641